Cell Density & Morphology Changes
Endothelial Morphology Examples
Normal Endothelial Cell Density (ECD)
Normal ECD declines with age.
Low ECD is a risk factor for cataract and corneal surgeries that can be missed without the use of specular microscopy.
Change from uniform cell sizes to variable cell sizes is an indication of distress to the endothelium.
Change from optimum hexagonal cell geometry to variable / compromised cell shapes.
Normal ECD with Polymegethism and Pleomorphism
Here the ECD is typical, but there are also large changes in morphology with high variance in cell area / sizes (pleomorphism) and a large number of non-hexagonal cell shapes (4, 5, 7 sided cells, i.e. pleomorphism).
Konan Medical is trusted to provide the most widely used specular microscopy – endothelial analysis tools for routine clinical practice, clinical trials, professional reading centers, and the world’s #1 eye bank system for qualification of donor corneal tissue.
This is not a coincidence, it has been and is continuously earned…only from Konan.
Konan CellChek Quick Tips
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